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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Melatonin potentiates arachidonate release stimulated by PGF2 alpha and by ionomycin.”
The Mel1a melatonin receptor is coupled to parallel signal transduction pathways.“ Melatonin significantly prevented the LPS‐induced rises in uterine prostaglandin (PG) E2, PGF2α , and cyclooxygenase‐2 protein levels.”
Melatonin prevents experimental preterm labor and increases offspring survival“Cumulative addition of melatonin (3–300 µM) caused a slowly developing relaxation in all three vascular preparations pre-contracted with 9,11-dideoxy-9a,11a-methanoepoxy prostaglandin F2α (U46619), a thromboxane mimetic agent.”
“ Melatonin (860 pmol/l), perfused either with PGF2 alpha or after PGF2 alpha, stimulated progesterone production.”
“Although melatonin alone is without effect on phosphoinositide hydrolysis, it potentiates the effects of PGF2α stimulation on phospholipase C activation.”
“ Melatonin potentiates arachidonate release stimulated by PGF2α and by ionomycin.”
The Mel1a Melatonin Receptor Is Coupled to Parallel Signal Transduction Pathways 1.
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