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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dinoprost
supplement:
Conjugated Linoleic Acid
Research Papers that Mention the Interaction
“The CLA diet resulted in increased lipid peroxidation measured as an 83% higher 8-iso-prostaglandin F2alpha concentration compared with the control, P < 0.0001.”
A diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young men.“Both n-3 polyunsaturated fatty acids (PUFAs) and conjugated linoleic acid CLA ) can alter biosynthesis of prostaglandins E(2) (PGE(2)) and prostaglandin F2α (PGF(2α)), which have critical roles in animal reproduction.”
A diet rich in n-3 polyunsaturated fatty acids reduced prostaglandin biosynthesis, ovulation rate, and litter size in mice.“In spite of stimulatory effects on PGHS-2 and peroxisome proliferator-activated receptor delta (PPARdelta) mRNA responses, CLA greatly decreased PGF2alpha production by PDBu-stimulated BEND cells.”
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