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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dinoprost
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“ ACTH (40-4000 pmol/L; n = 5) caused a dose-dependent reduction of both KC1 and PGF2alpha-induced increases in FAP in the fetal placental circulation.”
Adrenocorticotropin causes vasodilatation in the human fetal-placental circulation.“Output of PGF2 alpha by placental cells was increased in the presence of both CRH and ACTH.”
“The addition of PGF2 alpha to the culture medium containing ACTH resulted in a 80% decrease in F secretion, but PGE2 only suppressed F secretion by 50%.”
“Similarly, the administration of ACTH to castrated boars resulted in concomitant elevation of cortisol and PGF2α metabolite with peak levels reached at 60.0 ± 0.0 and 20.0 ± 0.0 min, respectively.”
Effect of ACTH and CRH on Plasma Levels of Cortisol and Prostaglandin F2α Metabolite in Cycling Gilts and Castrated Boars“Infusion of PGE1, PGE2 or PGF2 alpha (1 and/or 5 micrograms infused intracerebroventricularly) stimulated ACTH secretion.”
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