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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dimethyl Sulfoxide
supplement:
Tretinoin
Research Papers that Mention the Interaction
“ RA inhibits the GPI-80 expression on DMSO induced HL-60 cells suggests that different signal conduction has been activated by DMSO and RA when they induce the HL-60 cells to the neutrophilic differentiation.”
[Different impacts of DMSO and RA on GPI-80 expression].“Among various inducers of cell differentiation, 1,25(OH)2D3 and dimethylsulfoxide (DMSO) caused the increase of the NBT-reducing ability and the suppression of ALP activity induced by rhG-CSF, while RA enhanced both of them.”
“The addition of RA reduced the promotion of growth and increased the extent of terminal differentiation seen with HMBA and DMSO alone.”
“We found that combinations of RA with either NaB, HMBA, or DMSO synergistically induced terminal differentiation of HL60.”
“Simultaneous treatment with RA and DMSO proved synergistic with respect to morphological maturation and several functions (e.g. NBT reduction), but complementary stimulation of other activities (e.g. chemotaxis, lysozyme content) could not be demonstrated.”
“In contrast to aggregates that were treated with dimethylsulfoxide , the specific activity of pyruvate kinase was reduced after aggregation in the presence of retinoic acid.”
Phosphofructokinase and pyruvate kinase in mouse embryonal carcinoma P19 cells in relation to growth and differentiation.
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