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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dimethyl Sulfoxide and Tretinoin

Research Papers that Mention the Interaction

RA inhibits the GPI-80 expression on DMSO induced HL-60 cells suggests that different signal conduction has been activated by DMSO and RA when they induce the HL-60 cells to the neutrophilic differentiation.
Shi yan sheng wu xue bao  •  2005  |  View Paper
Among various inducers of cell differentiation, 1,25(OH)2D3 and dimethylsulfoxide (DMSO) caused the increase of the NBT-reducing ability and the suppression of ALP activity induced by rhG-CSF, while RA enhanced both of them.
Rinsho byori. The Japanese journal of clinical pathology  •  1992  |  View Paper
The addition of RA reduced the promotion of growth and increased the extent of terminal differentiation seen with HMBA and DMSO alone.
We found that combinations of RA with either NaB, HMBA, or DMSO synergistically induced terminal differentiation of HL60.
Cancer research  •  1990  |  View Paper
Simultaneous treatment with RA and DMSO proved synergistic with respect to morphological maturation and several functions (e.g. NBT reduction), but complementary stimulation of other activities (e.g. chemotaxis, lysozyme content) could not be demonstrated.
Cell differentiation  •  1987  |  View Paper
In contrast to aggregates that were treated with dimethylsulfoxide , the specific activity of pyruvate kinase was reduced after aggregation in the presence of retinoic acid.
Differentiation; research in biological diversity  •  1990  |  View Paper