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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dimethyl Sulfoxide
supplement:
Proline
Research Papers that Mention the Interaction
“Conclusions:It indicated that an appropriate concentration of L-proline can improve the cryopreservation efficiency of mouse oocytes with low concentrations of DMSO and EG, which may be applicable to human oocyte vitrification.”
“The survival rate of the postthawed oocyte in 2.00 mol/L L-proline combining 7.5% DMSO and 10% EG is significantly higher than that of the control group.”
Cryobiological Characteristics of L-proline in Mammalian Oocyte Cryopreservation“The addition of 2% DMSO and 200 mM proline significantly reduced the proportion of aggregates, but the addition of 1 mM 4‐PBA and 3% glycerol was hardly effective.”
“The incorporation of proline into bacterial collagenase digestible fractions was increased slightly in the DMSO group.”
“… proline has been reported to catalyze aldol … in polar solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), and while a small amount of water is beneficial in some proline-… aldol reactions, only low enantioselectivities have been obtained in water even in the presence of a surfactant.”
Combined proline-surfactant organocatalyst for the highly diastereo- and enantioselective aqueous direct cross-aldol reaction of aldehydes.
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