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“The affinity of the enzyme for 6-carboxypyrimidines was greatly increased in the presence of dimethylsulfoxide , but the rate of the enzyme-catalyzed reaction was markedly decreased.”
“The ab initio and BLYP calculations show that the complexation between nicotinamide (NA(Z) and NA(E)) and DMSO leads to large red shifts of the stretching vibrations for the hydrogen-bonded N-H bonds of nicotinamide and very strong increase in their IR intensity.”