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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dimethyl Sulfoxide
supplement:
Glucose
Research Papers that Mention the Interaction
“Mesangial cells, erythrocytes and peritoneal exudate cells incubated with DMSO showed enhancement of 14CO2 production from D-[1-14C] glucose but not from D-[6-14C] glucose.”
Dimethyl sulfoxide enhances hexose monophosphate shunt activity in cultured glomerular mesangial cells, leukocytes and erythrocytes.“ Dimethyl sulfoxide treatment altered the expression of genes involved in lipid (FAS, ACC1, ACC2, DGAT1, DGAT2, SCD) and glucose (PEPCK, G6Pase) metabolism as well as liver functionality (albumin, alpha‐1‐antitrypsin, AFP).”
“ DMSO treated animals had lower concentrations of glucose , creatine, phosphocholine and macromolecules compared to sham animals.”
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy“The inclusion of trehalose or glucose with DMSO further increased the post-thaw sperm motility (%) and plasma membrane integrity (PMI).”
“These findings suggest that DMSO given at low dose can prevent the decrease of hepatic glucose-6-phosphatase but may indirectly affect the level of tissue glucose.”
“In the intact intestine, intraluminal DMSO significantly decreased the net movement of water, electrolytes, and glucose without affecting either the active transport of phenylalanine and β-methylglucoside or morphology.”
“If glucose or galactose are present in the lumen in high initial concentrations, DMSO enhances the rate of absorption, and also changes the kinetics of transport from a saturation type (typical for carrier-mediated transport) to a diffusion type.”
“It is concluded that DMSO causes glucose and galactose to become sufficiently fat-soluble to bypass carrier mediation.”
“The enzyme catalyzed the dehydrogenation of glucose , in the presence of dimethylsulfoxide , with Km of 5 mM and Vmax 10% of that with glucose-6-phosphate.”
Purification and characterization of glucose-6-phosphate dehydrogenase from Cryptococcus neoformans: identification as "nothing dehydrogenase".“The effects of glucose and cAMP were enhanced by pre-incubating the cells in the presence of DMSO.”
“When suspended in a glucose medium supplemented with varying amounts of DMSO , ethylene glycol, glycerol, lactose and sodium chloride at its optimum temperature of 30 degrees C, a diploid strain of Saccharomyces cerevisiae gave a mean generation time inversely proportional to the increased concentrations of these anti-freeze compounds.”
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