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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dimethyl Sulfoxide and Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

DMSO … GABA at -60 mV. DMSO at 3% inhibited the GABA-induced inward and outward currents at -60 mV and +30 mV to similar extents (54% … suppressed the currents by interacting with GABA receptor-Cl- channel complex protein rather than by affecting the lipid-bilayer of the cell membrane.
Neuroscience Letters  •  1992  |  View Paper
DMSO alone (2-10% v/v) inhibited synaptosomal uptakes of GABA and of choline in a concentration-dependent fashion, with choline uptake inhibited to a greater degree than GABA uptake.
Neurotoxicology  •  1989  |  View Paper