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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Diltiazem and Vitamin D

supplement:

Vitamin D

Research Papers that Mention the Interaction

In rats the Ca antagonists verapamil and diltiazem not only prevented arterial calcinosis due to overdoses of vitamin D and dihydrotachysterol, but also counteracted age-dependent Ca accumulation.
Fortschritte der Medizin  •  1984  |  View Paper
The production of vascular changes and hemorrhages was inhibited by oral administration of a calcium antagonist, diltiazem (60 mg/kg-twice/day) for 7 days starting at the first day of vitamin D2 treatment.
Nihon juigaku zasshi. The Japanese journal of veterinary science  •  1984  |  View Paper
D3 and diltiazem (100 microM) inhibited cell proliferation, and diltiazem enhanced the D3-induced differentiation.
The concentration of free Ca2+ in the HL-60 cells following D3 and/or diltiazem treatment significantly increased.
Biochemistry international  •  1989  |  View Paper