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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Diltiazem
supplement:
Grapefruit Extract
Research Papers that Mention the Interaction
“The average individual increase in peak plasma concentration (Cmax) of diltiazem after grapefruit juice administration was 22±37%, but this effect was not statistically significant (P=0.14).”
Coadministration of grapefruit juice increases systemic exposure of diltiazem in healthy volunteers
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