supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Diltiazem
supplement:
Ellagic Acid
Research Papers that Mention the Interaction
“Gallic acid and ellagic acid significantly increased the bioavailability of diltiazem due to the inhibition of both CYP3A‐mediated metabolism and P‐glycoprotein‐mediated efflux in the intestine and/or liver.”
“The effective permeability of diltiazem was significantly enhanced in ileum part of gallic and ellagic acid‐treated groups.”
Enhanced Oral Bioavailability of Diltiazem by the Influence of Gallic Acid and Ellagic Acid in Male Wistar Rats: Involvement of CYP3A and P‐gp Inhibition
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback