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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Diindolylmethane
supplement:
Sulforaphane
Research Papers that Mention the Interaction
“Interestingly, at a total drug concentration of 2.5 microM, all combinations of SFN and DIM were antagonistic.”
“ SFN (10 microM) in combination with DIM (10 microM) resulted in strong G(2)/M cell-cycle arrest, which was not observed with either compound alone.”
Quantitative combination effects between sulforaphane and 3,3'-diindolylmethane on proliferation of human colon cancer cells in vitro.“ Sulforaphane from glucoraphanin can act synergistically with glucobrassicin-derived DIM and this may lead to opportunities for combinatorial approaches (supplement and food-based) in the clinic.”
Indoles Derived From Glucobrassicin: Cancer Chemoprevention by Indole-3-Carbinol and 3,3'-Diindolylmethane
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