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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dihydroxyphenylalanine and Tryptophan

Research Papers that Mention the Interaction

Tryptophan can inhibit DOPA (3,4-dihydroxy phenylalanine) conversion to melanin both by the enzymatic and the nonenzymatic route.
Experientia  •  2005  |  View Paper
The uptake of tryptophan is inhibited by high concentrations of phenylalanine, tyrosine, leucine and 3, 4‐dihydroxyphenylalanine.
Journal of neurochemistry  •  1983  |  View Paper
Phenylalanine, p-chlorophenylalanine, tyrosine, 3,4-dihydroxyphenylalanine and kynurenine as well as leucine, isoluecine and valine all inhibited the net uptake of tryptophan.
Journal of neural transmission. Supplementum  •  1979  |  View Paper