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Last Updated: 3 years ago

Possible Interaction: Dihydroxyphenylalanine and Thiamine

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drug:

Dihydroxyphenylalanine

supplement:

Thiamine

Research Papers that Mention the Interaction

“It was also observed that the percentage of thiamine disulfide formed from thiamine with some flavones, catechol, pyrogallol, caffeic acid, dihydroxyphenylalanine , and hemin is greater at pH 7.5 than at pH 7.0.”

Reactivation mechanisms of thiamine with thermostable factors.

Journal of nutritional science and vitaminology • 1976 | View Paper

“ Thiamine , added to tyrosine-tyrosinase reaction is assumed to act as follows: it interferes in the action of dopa or dopaquinone, inhibits the production of dopa, extends the lag period of this reaction, and is in itself oxidized to thiamine disulfide.”

Participation of thiamine and riboflavin in the formation of tyrosine melanin.

The Journal of vitaminology • 1960 | View Paper

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