Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Dihydrotestosterone and Tretinoin

Research Papers that Mention the Interaction

In additional studies, retinoic acid induced a dose-dependent … at concentrations of 0.1 to 1 microM. Dihydrotestosterone (10 nM.) also enhanced the secretion of PSA by … in a dose-dependent fashion by the addition of retinoic acid at 0.1-10 microM. Competitive … not bind to androgen receptors.
In the presence of 0.1 nM. dihydrotestosterone DHT ), LNCaP cell proliferation was inhibited by 10 microM. retinoic acid but not by lower concentrations of retinoic acid.
The Journal of urology  •  1993  |  View Paper
The conversion of testosterone to DHT by 5α‐reductase was reduced in the presence of retinoic acid.
The Prostate  •  1990  |  View Paper
These RAs also decreased [3H]thymidine labeling indexes of both epithelium and mesenchyme of SVs cultured in medium with DHT plus insulin or DHT alone and inhibited the increase in their protein contents.
Endocrinology  •  1996  |  View Paper