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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“The 1.5-h accumulation of digoxin and vinblastine in Caco-2 cells was significantly increased by 50 μM biochanin A or silymarin , and this effect was flavonoid-concentration dependent.”
Effect of the Flavonoids Biochanin A and Silymarin on the P-Glycoprotein-Mediated Transport of Digoxin and Vinblastine in Human Intestinal Caco-2 Cells“The apical to basolateral transport of digoxin was increased where as basolateral to apical transport of digoxin was decreased in concentration dependent manner in the presence of elacridar, quercetin and silymarin.”
Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs
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