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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Diethylstilbestrol
supplement:
Indole-3-Carbinol
Research Papers that Mention the Interaction
“Combination of I3C and DES enhanced the inhibitory effect on telomerase activity, gene expression, and cell viability.”
“ I3C at 250 μM combined with any concentration of DES was cytotoxic to LNCaP. Telomerase activity in PC3 cells with 250 μM of I3C and 25 or 50 μM of DES was significantly reduced or inhibited, respectively.”
“ I3C combined with DES reduced PC3 viability and eliminated LNCaP cells.”
“These results implied that I3C and DES combined might help in prostate cancer treatment.”
Indole-3-carbinol inhibits telomerase activity and gene expression in prostate cancer cell lines.
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