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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Vitamin C
Research Papers that Mention the Interaction
“The enzyme reaction was stimulated by Cu(II) ion and ascorbic acid and inhibited by the presence of diethyldithiocarbamate.”
Characterization of a substance P-Gly12 amidating enzyme in human cerebrospinal fluid.“ Ascorbic acid , cimetidine, and nifedipine pretreatments were found to induce highly protective effects against the evinced DDC hepatotoxicity, manifesting that free radical, cytochrome P450, and calcium-dependent processes contribute to DDC liver toxicity.”
The protective effects of ascorbic acid, cimetidine, and nifidipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats“It was found … when both DDC (… AsA (2 x 10(-5) M approximately 2 x 10(-4) M) were added simultaneously and cultured for 48 h. A similar … h and cultured for 48 h. The augmented inhibitory effect was completely inhibited by the addition of catalase (2000 U/ml).”
“Thus a marked augmentation of the inhibitory effect was observed when DDC and AsA were used in combination.(ABSTRACT TRUNCATED AT 250 WORDS)”
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