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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cupric Cation
Research Papers that Mention the Interaction
“Diethyldithiocarbamate DDC ) has been shown to inhibit SOD activity by chelating Cu2+ , the metal ion essential for the catalytic activity of the enzyme.”
Establishment of the interferon-mediated antiviral state: possible role of superoxide dismutase.“The cyclovoltammetry patterns of DDC were drastically changed either by Cu2+ , Co2+ or by Cd2+ suggesting a strong interaction of the metals with DDC.”
“The enzyme reaction was stimulated by Cu(II) ion and ascorbic acid and inhibited by the presence of diethyldithiocarbamate.”
“Preincubation of DDC with Cu++ or Zn++ failed to neutralize its inhibitory effects nor could function be restored in DDC-pretreated NK cells by subsequent addition of Cu++, Zn++, Mg++, or Ca++.”
“The ultraviolet-visible (UV-Vis) absorption spectra indicated that DDTC formed a complex with Cu2+ , showing a prominent peak at ~450 nm.”
“The procedure utilizes the capacity of diethyldithiocarbamate to react with cupric ions resulting in a complex of dark yellow color.”
Colorimetric determination of agarose-immobilized proteins by formation of copper-protein complexes.
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