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“Charge movements measured around mechanical threshold in muscle fibres bathed in hypertonic solutions were reduced when 2 mM‐tetracaine was added to the bathing fluid.”
“ Muscle fibres bathed in hypertonic solutions containing 2 mM‐tetracaine were rapidly depolarized.”
“ Tetracaine (0.05‐0.2 mM) stopped contraction in every sternomastoid fibre examined (n = 9) and reduced the asymmetric charge (moved by depolarizing steps to 0 mV) by 15% (S.E. of mean 3%).”
“ Amethocaine , an agent of high lipid solubility, blocked A fibres more quickly than C. As lipid solubility decreased through the series studied, so the onset of conduction blockade of A fibres was prolonged.”