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“ Rapamycin also impaired cell mobility, as assessed by a wound test, and promoted the formation of actin stress fibres , as determined with confocal microscopy.”
“Pretreatment of cells with rapamycin , to inhibit p70s6k activation, inhibits thrombin-induced stress fibre formation and the associated presence of p70s6k on the fibres , supporting a role for p70s6k in thrombin-stimulated stress fibre formation.”