supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Dietary Fiber
drug:
Digoxin
Research Papers that Mention the Interaction
“The effect of fibre alone is small but an interactive effect on absorption may occur if fibre and digoxin are ingested simultaneously.”
Effect of administration of activated charcoal and fibre on absorption, excretion and steady state blood levels of digoxin and digitoxin. Evidence for intestinal secretion of the glycosides.“Alteration of the timing of the administration of digoxin from that …. as with liquid antacids, kaolin-pectin, or meals of high fibre content), or alteration of the dose of digoxin based on the anticipated change … or medications altering gut function or motility), can improve clinical effectiveness of digoxin therapy.”
“The difference in digoxin binding to the two fibre types may explain, at least partly, the interindividual variations in the binding of digoxin to skeletal muscle.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback