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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Didanosine and Levocarnitine

supplement:

Levocarnitine

Research Papers that Mention the Interaction

Apoptotic CD4 and CD8 cells, lymphocytes with disrupted mitochondrial membrane potential, and lymphocytes undergoing oxidant stress were greatly reduced in subjects treated with AZT and DDI plus L-carnitine compared with those who did not receive L-carnitine.
Antioxidants & redox signaling  •  2002  |  View Paper
On … hand l-carnitine , in association with the mitochondrial cardiolipins, inhibits myopathy … continued prescription of drugs [AZT (zidovudine), ddl ( didanoside ), or ddC (zalcitabine)], and the redox couple of α-lipoic-dihydrolipoic acid prevents production of … reactive oxygen species that trigger apoptosis of infected cells, with sphingomyelin breakdown to ceramides.
Lipids  •  2007  |  View Paper
Studies show that d4T and ddI may cause neuropathy by lowering L-acetyl-carnitine levels; however, there have been no controlled studies showing that L-acetyl-carnitine therapy is effective.
Notes from the underground  •  1997  |  View Paper