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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Diclofenac and Vitamin B Complex

Research Papers that Mention the Interaction

According to the high consumption of the mixture of B vitamins and diclofenac in several countries, this combination has constituted a frequently used option in pain therapy from inflammatory origin.
Drug research  •  2013  |  View Paper
There is evidence that B vitamins are able to increase the antinociceptive activity of diclofenac in animals [5,6].
Proceedings of the Western Pharmacology Society  •  2002  |  View Paper
In particular, the pain relief obtained with antiinflammatory drugs such as diclofenac was enhanced when B vitamins were simultaneously given in patients with low back pain.*
Annals of the New York Academy of Sciences  •  1990  |  View Paper
In this sense, the combination of diclofenac with the B vitamins was particularly effective in achieving both of these goals.
Journal of drug assessment  •  2016  |  View Paper
In the present special issue, a study realized by H. A. Ponce-Monter et al. showed that the diclofenac plus B vitamins combination was more effective to reduce the pain than diclofenac alone.
Pain research and treatment  •  2012  |  View Paper
Diclofenac plus B vitamins combination was more effective to reduce the pain than diclofenac alone.
The results showed that the addition of B vitamins to diclofenac increased its analgesic effect.
Pain research and treatment  •  2012  |  View Paper
It is also worth noting that the B vitamins are shown to enhance the beneficial effect of diclofenac in acute low-back pain so that either the duration of treatment or the daily dose of diclofenac may be reduced.
Schmerz  •  1998  |  View Paper
Similarly, B vitamins potentiate the therapeutic effect of diclofenac in patients suffering from acute low back pain.
Schmerz  •  1992  |  View Paper