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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Diclofenac
supplement:
Vitamin B Complex
Research Papers that Mention the Interaction
“According to the high consumption of the mixture of B vitamins and diclofenac in several countries, this combination has constituted a frequently used option in pain therapy from inflammatory origin.”
B-vitamin mixture improves the analgesic effect of diclofenac in patients with osteoarthritis: a double blind study.“There is evidence that B vitamins are able to increase the antinociceptive activity of diclofenac in animals [5,6].”
B vitamins increase the anti-hyperalgesic effect of diclofenac in the rat.“In particular, the pain relief obtained with antiinflammatory drugs such as diclofenac was enhanced when B vitamins were simultaneously given in patients with low back pain.*”
“In this sense, the combination of diclofenac with the B vitamins was particularly effective in achieving both of these goals.”
Comparison of the action of diclofenac alone versus diclofenac plus B vitamins on mobility in patients with low back pain“In the present special issue, a study realized by H. A. Ponce-Monter et al. showed that the diclofenac plus B vitamins combination was more effective to reduce the pain than diclofenac alone.”
“ Diclofenac plus B vitamins combination was more effective to reduce the pain than diclofenac alone.”
“The results showed that the addition of B vitamins to diclofenac increased its analgesic effect.”
“It is also worth noting that the B vitamins are shown to enhance the beneficial effect of diclofenac in acute low-back pain so that either the duration of treatment or the daily dose of diclofenac may be reduced.”
“Similarly, B vitamins potentiate the therapeutic effect of diclofenac in patients suffering from acute low back pain.”
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