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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Diclofenac
supplement:
Glutathione
Research Papers that Mention the Interaction
“Co-incubation of mitochondria with Dic and reduced GSH exhibited a protective effect on Dic mediated inhibition of ATP synthesis.”
Mitochondrial toxicity of diclofenac and its metabolites via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria: Possible role in drug induced liver injury (DILI).“Incubation of hepatocytes with diclofenac caused rapid hepatocyte glutathione ( GSH ) depletion which is another marker of cellular oxidative stress.”
Involvement of Lysosomal Labilisation and Lysosomal/mitochondrial Cross-Talk in Diclofenac Induced Hepatotoxicity
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