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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dibucaine
supplement:
Phenylalanine
Research Papers that Mention the Interaction
“From these results it was … that: the aromatic ring of phenylalanine of MP-1A and the aromatic … of the cationic form of dibucaine or lidocaine are interacting by pi-pi stacking; the tertiary amine nitrogen of … is interacting electrostatically with D1487, whereas that of lidocaine is interacting with E1492.”
Interactions between local anesthetics and Na+ channel inactivation gate peptides in phosphatidylserine suspensions as studied by 1H-NMR spectroscopy.“It was found that the quinoline ring of dibucaine can interact with the aromatic ring of Phe by stacking of the rings; moreover, the interaction can be reinforced by the presence of lipids.”
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