Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Diazoxide and Glucose

supplement:

Glucose

Research Papers that Mention the Interaction

No statistically significant differences were observed between the groups concerning the … absolute weight or glycosylated hemoglobin after 2 months, but the plasma glucose concentrations (basal and after OGTT) … greater in the patients receiving DZX treatment vs those receiving the placebo, whereas the … increases in insulin after OGTT were lower.
The Journal of clinical endocrinology and metabolism  •  2016  |  View Paper
In cultures at 27 mmol/l glucose , the presence of diazoxide decreased the PI/I ratio of islet contents by 76%, the accumulated secretion to culture medium by 70%, and the release at 3.3 or 16.7 mmol/l glucose during postculture incubations by 85 and 86%, respectively.
Diabetes  •  1999  |  View Paper
The first method, in the presence of diazoxide , blocked the action of glucose on the K(ATP) channel in combination with a depolarizing concentration of KCl to raise [Ca2+]i.
Diabetes  •  1998  |  View Paper
Modulation of insulin-secretory activity of BRIN-BD11 cells by co-culture at high glucose with diazoxide.
The Journal of endocrinology  •  1997  |  View Paper
Plasma glucose levels were increased during diazoxide treatment in six patients necessitating interruption of this therapy in four patients.
Klinische Wochenschrift  •  1980  |  View Paper
However, the need for exogenous glucose is reduced with the concomitant use of diazoxide.
Southern medical journal  •  1978  |  View Paper
In the presence of glucose , insulin release increased and diazoxide and epinephrine inhibited this glucose effect.
The Journal of clinical endocrinology and metabolism  •  1973  |  View Paper
~ , ~ Frerichs and associate^,^ and Howell and TaylorE have shown by in vifro experiments that diazoxide causes an inhibition of insulin secretion induced by glucose.
Annals of the New York Academy of Sciences  •  1968  |  View Paper
It is suggested that diazoxide , directly or indirectly, inhibits hepatic glucose uptake.
Diabetes  •  1966  |  View Paper
Glucose injection at the rat dorsal root ganglia (L5) resulted in acute mechanical hyperalgesia that was blocked by diazoxide.
Journal of the Neurological Sciences  •  2019  |  View Paper
Show More