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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Diazoxide and Gamma-Aminobutyric Acid

drug:

Diazoxide

supplement:

Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

“ Diazoxide caused a twofold greater decrease in GABA levels, and glybenclamide increased VMH GABA levels by 57%.”
ATP-Sensitive K+ Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia
Diabetes  •  2007  |  View Paper
“ Diazoxide , a sulfonylurea receptor 1 (SUR1)selective KATP-channel opener, prevented DA modulation by H2O2, glutamate, and GABA , whereas cromakalim, a SUR2-selective opener, did not.”
Activation of ATP-sensitive K+ (KATP) channels by H2O2 underlies glutamate-dependent inhibition of striatal dopamine release
Proceedings of the National Academy of Sciences of the United States of America  •  2003  |  View Paper
“ Diazoxide and cromakalim decreased the K(+)-evoked release of [3H]GABA from pallidal slices.”
Modulation of GABA Transmission by Diazoxide and Cromakalim in the Globus Pallidus: Implications for the Treatment of Parkinson's Disease
Experimental Neurology  •  1996  |  View Paper