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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Diazoxide and Calcium Supplement

Research Papers that Mention the Interaction

This characteristic distinguishes them from other drugs such as sodium nitroprusside, papaverine, hydralazine and diazoxide which interfere with the availability of calcium ions for their physiological functions by acting at sites other than the 'calcium channels'.
Drugs  •  1983  |  View Paper
This characteristic distinguishes them from other drugs such as sodium nitroprusside, papaverine, hydralazine and diazoxide which interfere with the availability of calcium ions for their physiological functions by acting at sites other than the ‘calcium channels’.
Drugs  •  2012  |  View Paper
Pretreatment with diazoxide resulted in a significant intracellular Ca and Mg loss in each experimental situation.
Acta Diabetologica  •  2006  |  View Paper
Infusion of diazoxide (600 mg) with calcium blocked the stimulation of the latter on insulin secretion.
Metabolism: clinical and experimental  •  1979  |  View Paper
It is suggested that diazoxide may act by displacing calcium at the receptor site, since its relaxant effect resembles the rapid response of magnesium and prevents the action of oxytocin.
American journal of obstetrics and gynecology  •  1968  |  View Paper
A slight delay in Ca2+ -induced swelling of the mitochondria exposed to diazoxide could be result of an inhibition of succinate oxidation by the mitoKATP modulator.
Journal of Bioenergetics and Biomembranes  •  2015  |  View Paper
This facilitation of the outward transport of calcium might explain why diazoxide inhibits the stimulant action of glucose upon calcium accumulation in the beta cell.
Diabetologia  •  2005  |  View Paper
A … that DA activates ATP-dependent K + channels in the inner mitochondrial membrane [2], increases … the proton permeability of the inner mitochondrial membrane [2, 3], inhibits Ca 2 + influx and stimulates Ca 2+ efflux from the mitochondrial matrix [2, … the transmembrane potential ( ∆Ψ ) on the inner mitochondrial membrane [2].
Doklady Biochemistry and Biophysics  •  2004  |  View Paper
Under these conditions, mitoKATP channel activity strongly regulated Δψm, and diazoxide prevented MPT by inhibiting the driving force for Ca uptake.
Proceedings of the National Academy of Sciences of the United States of America  •  2002  |  View Paper
The effect of glucose on beta-cell spreading was mimicked by 25 mmol/l KCl (which induces calcium influx) and inhibited by diazoxide (which impairs depolarization and calcium entry ) and by the L-type Ca2+ channel blocker SR-7037.
Diabetes  •  2001  |  View Paper
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