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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Diazepam
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“To potentiate the antidotal effects of pyridoxine, diazepam (0.1 mg/kg) may be given intravenously, preferably at a second intravenous site.”
Emergency department management of children with acute isoniazid poisoning.“All drugs had a protective effect but combinations containing diazepam and either pyridoxine or muscimol were the most effective antagonists to MMH convulsions and death.”
Therapeutics of monomethylhydrazine intoxication.“Although correction of acidosis increases the antidotal effectiveness of diazepam plus pyridoxine , increasing the dose of either or both of these two drugs achieves the same antidotal advantage without the potential problems of metabolic alkalosis which may result from NaHCO 3 administration.”
“Combined administration of diazepam with pyridoxine protected against convulsions and death in rats and dogs.”
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