supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Induction or augmentation of labor with oxytocin was associated with decreased serum protein binding of diazepam and possibly of bilirubin in mothers.”
Serum protein binding of drugs and bilirubin in newborn infants and their mothers“Because oxytocin and diazepam act on GABAergic transmission, it is possible that oxytocin can potentiate the inhibitory effects of diazepam if both exert their pre, - respectively postsynaptic effects on the same inhibitory circuit in the central amygdala.”
“These findings show that oxytocin and diazepam act on different components of the same GABAergic circuit in the central amygdala and that oxytocin can facilitate diazepam effects when used in combination.”
Oxytocin enhances the inhibitory effects of diazepam in the rat central medial amygdala“On the other hand, GABA, GABAB receptors agonist phenibut and diazepam inhibit the stimulating effects of the above mentioned substances, thus showing the properties of physiological antagonists of these neuromediators, prostaglandin and oxytocin.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback