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Discover Supplement-Drug Interactions

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Last Updated: 7 months ago

Possible Interaction: Dianhydrogalactitol and Vitamin E

Research Papers that Mention the Interaction

We have reported that d-alpha-tocopherol can prevent hyperglycemia-induced activation of DAG and PKC levels in vascular tissues as well as normalizing retinal blood flow and renal hyperfiltration.
Diabetes research and clinical practice  •  1999  |  View Paper
The presence of d-alpha-tocopherol (50 micrograms/ml) prevented the increase of both total DAG and [3H]-palmitate labeled DAG levels in cells exposed to 22 mM glucose.
BioFactors  •  1998  |  View Paper
D-α-tocopherol prevented the glucose-stimulated increases in DAG level and PKC activity as well as the amount of PKC βII isoform in ASMCs cultured with elevated glucose levels.
Intraperitoneal injection of D-α-tocopherol (40 mg/kg) every other day resulted in a significant decrease of the elevated membranous PKC specific activity and total DAG levels in parallel with a significant increase of D-α-tocopherol content in the aorta.
Diabetes  •  1996  |  View Paper