Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Dextromethorphan and Melatonin

Research Papers that Mention the Interaction

Postnatal DEX decreased protein level of MT2 in the kidney, which was attenuated by melatonin therapy.
We found DEX group developed hypertension at 16 weeks of age, which melatonin therapy prevented.
Steroids  •  2016  |  View Paper
Neonatal DEX exposure induced hypertension in male offspring at 16 weeks of age, which melatonin prevented.
The Journal of Steroid Biochemistry and Molecular Biology  •  2014  |  View Paper
However, the combined intraperitoneal administration of melatonin (30 mg/kg) and DM (15 mg/kg) effectively reversed both thermal hyperalgesia and mechanical allodynia although each individual dose alone did not reduce pain behaviors.
Brain Research  •  2009  |  View Paper