supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Dextromethorphan
supplement:
Lysine
Research Papers that Mention the Interaction
“Reversal of the Glu-216 charge to Lys or substitution with neutral residues (Gln, Phe, or Leu) greatly decreased the affinity (K m values increased 10–100-fold) for the classical basic nitrogen-containing substrates bufuralol and dextromethorphan.”
Residues Glutamate 216 and Aspartate 301 Are Key Determinants of Substrate Specificity and Product Regioselectivity in Cytochrome P450 2D6*
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback