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Last Updated: 2 years ago

Possible Interaction: Dextroamphetamine and Vitamin C

supplement:

Vitamin C

Research Papers that Mention the Interaction

The behavioural excitation induced by d-amphetamine (2.5 mg/kg SC) was significantly potentiated by ascorbic acid (100–200 mg/kg IP).
Psychopharmacology  •  2004  |  View Paper
AA also reduced locomotor activity produced by d-amphetamine and methanol.
Pharmacology Biochemistry and Behavior  •  1999  |  View Paper
Since it is well … systemic administration of AsAc … d-A behavioral effects, it is suggested, as a working hypothesis, that the d-A CNS stimulating effect may cause a recruitment … AsAc, whose task could be a negative neuromodulatory action on the overall effect of d-A on neuronal activity.
at the dose of … consecutive days, significantly increased AsAc levels by 26% in HYP (P less than 0.005), by 14% in ST (P less than 0.05), … than 0.001), as opposed to untreated rats; return of AsAc toward baseline levels was negligible 24 hours after d-A ….
Pharmacological research communications  •  1988  |  View Paper
In other experiments, 500 mg/kg of ascorbic acid given to mice 1 hour prior to the dopamine releasing agent d-amphetamine , was able to greatly attenuate the increase in locomotor activity usually seen after amphetamine.
Research communications in chemical pathology and pharmacology  •  1981  |  View Paper