Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Dextroamphetamine and Tyrosine

supplement:

Tyrosine

Research Papers that Mention the Interaction

We have recently reported the ability of L-tyrosine (L-TYR) to potentiate the anorectic activity of various mixed-acting sympathomimetics including phenylpropanolamine (PPA), l-ephedrine (EPH) and d-amphetamine (AMP).
Pharmacology Biochemistry and Behavior  •  1991  |  View Paper
Increases in motor activity following low doses of amphetamine (0.75-1.5 mg/kg) in casein control mice were antagonized by dietary L-tyrosine, but a higher dose of d-amphetamine (3 mg/kg) interacted with the addition of L-tyrosine producing an increase in motor activity.
Pharmacology Biochemistry and Behavior  •  1990  |  View Paper
L-TYR (200 mg/kg) significantly potentiated the anorectic activity of phenylpropanolamine, (-)-ephedrine and (+)-amphetamine by 48, 50 and 37%, respectively.
The Journal of pharmacology and experimental therapeutics  •  1990  |  View Paper
This was correlated with an attenuation in the ability of (+)-amphetamine to stimulate [3H]dopamine formation from [3H]tyrosine in rat striatal slices of these nicotine-treated animals.
Pharmacology Biochemistry and Behavior  •  1989  |  View Paper