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Last Updated: 3 years ago

Possible Interaction: Dextroamphetamine and Tetrahydrocannabinol (THC)

Research Papers that Mention the Interaction

Also, the hyperthermia caused by 5 mg/kg d-amphetamine is antagonized by THC , whereas the d-amphetamine induced stereotype movements (above 4 mg/kg) are prolonged by the cannabinoid.
Psychopharmacology  •  1977  |  View Paper
Chronic Delta9-THC decreased locomotor activity before and after dexamphetamine administration suggesting functional antagonism of the locomotor stimulant effect.
The international journal of neuropsychopharmacology  •  2010  |  View Paper
Delta(9)-Tetrahydrocannabinol fully prevented the oxidative effect of AMPH and MDMA, by a CB(1) receptor-independent mechanism, as did it NPC 15437 and genistein.
Neurochemistry International  •  2008  |  View Paper
The effects of Δ9 THC were antagonized by the administration of (+)-amphetamine in doses of 2.5 mg kg i.v.
Neuropharmacology  •  1972  |  View Paper
The present results reveal that female Δ9-THC exposure during adolescence can diminish the reward-facilitating effects of Δ9-THC and d-amphetamine in the adult male offspring.
The reward-facilitating effects of 0.5 and 1 mg of d-amphetamine were significantly decreased in the F1 offspring of females that were exposed to Δ9-THC (1 mg/kg and 0.1 or 1 mg, respectively).
Front. Pharmacol.  •  2017  |  View Paper