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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dextroamphetamine
drug:
Spiperone
Research Papers that Mention the Interaction
“Scopolamine reversed the reduction in avoidance responding caused by spiperone and antagonized the inhibitory effects of spiperone on the behavioral actions of d-amphetamine or apomorphine.”
Behavioral and biochemical studies of the scopolamine-induced reversal of neuroleptic activity“The expression of d-amphetamine CPP was significantly inhibited by SCH23390 (0.08, 0.16 mg/kg) and spiperone (0.15 mg/kg) when given alone before the post-conditioning test session.”
“In striatum, D-amphetamine produces a down-regulation of [3H]spiroperidol binding but an increase in [3H]ADTN bound (measured in the absence of ascorbate).”
“On the other hand, spiperone tended to antagonise the anorectic actions of mazindol and (+)-amphetamine by reversing the severe reduction in feeding duration produced by these two drugs.”
Effects of spiperone alone and in combination with anorectic agents on feeding parameters in the rat
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