Possible Interaction: Dextroamphetamine and Propranolol

“Low doses of d-amphetamine plus propranolol rapidly improved the abdominal pain in 165 "spastic colon" patients.”

“ Propranolol and betaxolol increased the hyperlocomotion produced by d-amphetamine and methylphenidate.”

“The stimulation produced in dexamphetamine-(but not in vehicle-) treated mice by dexamphetamine was partially blocked by phentolamine, phenoxybenzamine, and propranolol.”

“ResultsThe psychomotor stimulant effect of d-amphetamine , but not that of cocaine or apomorphine, was dose-dependently inhibited by clonidine and prazosin, and enhanced by propranolol.”

“The α2 antagonist idazoxan and the β antagonist propranolole , however, failed to prevent d-amphetamine from producing the excitation.”

“The efficacy of diazepam, haloperidol, propranolol , and yohimbine in antagonizing the toxic manifestations of d-amphetamine were studied in rats.”

“Further, several compounds including imipramine and propranolol , without known anorectic properties were among the most potent agents to inhibit [3H](+)-amphetamine binding.”

“In a set of experiments we checked the effect of two beta-blocker agents: oxprenolol and dl-propranolol, and the effect … and apomorphine at an ambient temperature of 4 degrees C. It was found that the two beta-blockers and the d-propranolol … d-amphetamine and apomorphine, … dopaminergic system.”

“In combination with propranolol d-amphetamine was toxic to developing mice and potentiated the hypothermia.”

“The effect of d-amphetamine and noradrenaline was blocked by propranolol , a β-adrenergic blocking agent but not by the α-adrenergic blocking agent phentolamine.”