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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dextroamphetamine
drug:
Promethazine
Research Papers that Mention the Interaction
“ Promethazine is a vestibular suppressor, but study results show that d-amphetamine counterbalances this depression and abolishes the effect of fatigue on the saccadic reaction time The hypothesis that a SCC-suppression alleviates SMS should be further evaluated.”
“ Promethazine … d-amphetamine decreased the latency of the saccadic eye response (right eye: 185 +/- 3.8 ms vs. 165 +/- 4.5 ms; left eye: 181 +/- 4.…) and also increased the phase of ocular counterrolling measured during unilateral centrifugation (0.32 +/- 0.35 degrees vs. 1.5 +/- 0.45 degrees).”
“A statistically significant decrement of performance scores was seen with scopolamine 1 mg or 0.8 mg, and with … 25 mg I.M. The combination of promethazine 25 mg with scopolamein 0.4 mg, and that of promethazine 25 mg ….M. with d-amphetamine 10 mg, also … placebo scores.”
“However, there was a statistically significant left-right asymmetry after intake of the combination promethazine + d-amphetamine for the parameters p13 and latency difference.”
No Effects of Anti-Motion Sickness Drugs on Vestibular Evoked Myogenic Potentials Outcome Parameters“Subjects who received a combination of promethazine plus d-amphetamine were able to suppress vestibular eye movements and maintain good visual fixation under the task condition.”
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