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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dextroamphetamine
drug:
Physostigmine
Research Papers that Mention the Interaction
“The effects on this behavior of mixing d-amphetamine or methylphenidate with scopolamine or physostigmine suggest that this opposed action on rearing response duration is related to cholinergic-catecholaminergic balance.”
Cholinergic modulation of an opposed effect of d-amphetamine and methylphenidate on the rearing response“Concurrent administration of drugs revealed that reserpine effectively reversed the effects of scopolamine, while the perseveration induced by d-amphetamine was antagonized by physostigmine.”
“The predominant effect of arecoline, physostigmine and carbachol was also to potentiate d-amphetamine.”
“Scopolamine (5 mg/kg, IP) blocks both spontaneous and D-amphetamine induced H-S. Physostigmine (0.10 mg/kg, IP), but not neostigmine, increases D-amphetamine induced H-S up to 400%.”
“Significant qualitative differences were found between the I.C. effects of d-amphetamine (15 mug) and dopamine (15-90 mug): d-amphetamine further increased the intensity of ongoing tremors induced by physostigmine (111 mug I.C.), whereas, dopamine readily inhibited the latter.”
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