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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dextroamphetamine and Ondansetron

Research Papers that Mention the Interaction

In subjects with minimal or moderate activation/euphoria responses, ondansetron pretreatment only minimally affected these effects of D-amphetamine.
Psychiatry Research  •  1996  |  View Paper
As ondansetron , a 5-HT3 receptor antagonist and modulator of cortico-mesolimbic dopamine function, has been shown to reduce some of the rewarding effects of d-amphetamine in animal and human laboratory studies, we decided to test whether it would be superior to placebo at reducing methamphetamine use.
The international journal of neuropsychopharmacology  •  2008  |  View Paper
Ondansetron was administered 30 minutes prior to d-amphetamine (3 mg/kg, i.p.).
Indian journal of physiology and pharmacology  •  2000  |  View Paper
It is suggested that ondansetron has two opposing effects on intake, one of which (hyperphagia) can be masked by d-amphetamine , leaving an anorectic effect that augments that of d-amphetamine.
Pharmacology Biochemistry and Behavior  •  1993  |  View Paper