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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dextroamphetamine
drug:
Nicotine
Research Papers that Mention the Interaction
“These findings indicate that environmental enrichment can limit the ability of adolescent nicotine exposure to increase vulnerability to other psychostimulant drugs, such as d-amphetamine.”
Effects of Environmental Enrichment on d-Amphetamine Self-Administration Following Nicotine Exposure“30 min before nicotine blocked sensitization of both locomotion and DA overflow in response to AMPH challenge.”
“We previously demonstrated in female, Holtzman rats that one low dose of nicotine will potentiate locomotor activity and dopamine (DA) efflux in response to a subsequent low dose of d-amphetamine (AMPH) given 1-4 h later.”
“of nicotine 2-4 h before a challenge with AMPH (0.32 mg/kg, i.p.)”
“We observed cross-tolerance to the anxiogenic effects of d-amphetamine and nicotine that was blunted by a pretreatment with calcium channel blockers.”
“ d-Amphetamine and nicotine dose dependently decreased hits and increased misses at doses that did not impair rates of responding.”
Effect of pentobarbital, d-amphetamine, and nicotine on two models of sustained attention in pigeons“Pretreatment with nicotine (0.4 mg/kg SC daily for 5 days) caused sensitisation of the locomotor responses to D-amphetamine (0.1–0.5 mg/kg SC) but not cocaine (15 mg/kg IP).”
“Both (-)-nicotine and (-)-nornicotine showed partial substitution (approximately 50% drug-appropriate responding) for the (+)-amphetamine training dose, with (-)-nicotine being more potent than (-)-nornicotine.”
“The … (+)‐amphetamine (0.5 mg kg−1 30 min before the … lever‐pressing in rats trained with saline or nicotine and abolished the increase in the number of shocks received by the nicotine‐withdrawn rats, … no significant effect on the number of shocks received by rats trained with saline.”
“Short-term (1-day) administration of nicotine to rats reduced the stimulatory effect of (+)-amphetamine on locomotor activity.”
“Stimulants such as d-amphetamine are misused more by women and are commonly co-used with nicotine.”
“When d-amphetamine was coadministered with nicotine , we found an interaction effect on reward enhancement that persisted across schedules of reinforcement.”
“ d-Amphetamine potentiates nicotine ’s effects in human and animal research.”
Reward-enhancing effects of d-amphetamine and its interactions with nicotine were greater in female rats and persisted across schedules of reinforcement“In the second experiment, the cueing effects of d-amphetamine were potentiated by nicotine and attenuated by morphine and midazolam.”
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