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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dextroamphetamine
drug:
Kynurenic Acid
Research Papers that Mention the Interaction
“As shown previously in adult rats, glucose removal and d-amphetamine (d-Amph) administration caused decreases in KYNA formation, while exposure to pyruvate up-regulated KYNA synthesis.”
Modulation and function of kynurenic acid in the immature rat brain.“At all ages, KYNA levels were significantly reduced 1 h after the systemic administration of D-AMPH (5 mg/kg).”
“In the adult brain, d-amphetamine caused a transient, dose-dependent decrease in tissue content and extracellular levels of KYNA , reaching a nadir of approximately 70% of control values after 1 h at 5 mg/kg.”
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