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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Dextroamphetamine
drug:
Hydrocortisone
Research Papers that Mention the Interaction
“In normal subjects, lo-20 mg oral dextroamphetamine causes an increase in plasma cortisol at a time when a decrease would be consistent with the normal diurnal variation (Brown et al. 1978).”
The effect of oral dextroamphetamine on plasma cortisol in major depressive disorder“In 24 male subjects oral dextroamphetamine 20 mg caused a statistically significant rise in cortisol , prolactin, TSH, FSH, and LH compared to placebo.”
“Lisdexamfetamine and d-amphetamine significantly enhanced plasma levels of adrenocorticotropic hormone, glucocorticoids ( cortisol , cortisone, corticosterone, 11-dehydrocorticosterone, and 11-deoxycortisol), androgens (dehydroepiandrosterone, dehydroepiandrosterone sulfate, and Δ4-androstene-3,17-dione [androstenedione]), and progesterone (only in men) compared with placebo.”
“RESULTS As expected, both stress and d- mphetamine in creased cor tisol, h eart rate and blood pressure.”
“ d-amphetamine increased heart rate, blood pressure and plasma cortisol levels while inducing psychostimulant-type subjective effects.”
“Plasma cortisol levels rose significantly at 1 and 2 hours after d-amphetamine compared to following placebo.”
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