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“The spatio-temporal properties of Ca2+ sparks were slightly affected by altering [K+]i (50-200 mmol/L) in saponin permeabilized myocytes in the presence of 8% dextran.”
“However, the lysis that occurred upon 30 min continuous incubation with the saponin could be inhibited (delayed) by the addition of an osmotically active compound - a dextran.”