Possible Interaction: Dexamethasone and Vitamin E

“The combinations of dexamethasone or minocycline with NAC and vitamin E increased the AFB1 concentrations in the plasma and all tissues, except for vitreous humor and liver.”

“In summary, VC, VE , especially their combination alleviate the oxidative stress induced by DEX and are favorable for the fertility of breeder roosters.”

“Results: VitE and DEX in simultaneous form of administration significantly (P<0.05) down-regulated the tissue ALP level and attenuated the VCL-decreased GSH-px, SOD and TAC levels and remarkably (P<0.05) down-regulated the testicular malondialdehyde (MDA) and nitric oxide (NO) contents.”

“The VitE and DEX co-administration reduced the VCL-increased RNA damage and elevated the Leydig cells steroidogenic activity.”

“ Vitamin E administration to Hp 2-2 DM mice resulted in a significant decrease in both intralysosomal iron-induced oxidation and lysosomal destabilization.”

“CONCLUSIONS Vi amin E co mbined with low dose of DXM co uld effectively inhibit inflammation and expression of MLCK protein in acute lung injury induced by LPS lung.”

“Treatment with a combination of alpha-toc and a suboptimal dose of 0.5 mg/kg dexamethasone enhanced the effect, suggesting that alpha-toc, in combination with low doses of corticosteroids, might be effective for therapeutic treatment of acute lung injury.”

“Palm vitamin E improved femoral length and calcium content in the Dexamethasone treated animals.”

“ DEX treatment also had no effect on hepatic AA content but decreased alpha-T concentrations in the liver.”

“Even with a high vitamin E offer, Se deficiency (less than 38 micrograms/kg DM of the ration) led to a 33% lower conception rate (P less than 0.05) in goats and to a greater than 50% lower number of kids on the 91st day of life.”

“Butyrated hydroxyanisole, butyrated hydroxytoluene and alpha-tocopherol significantly inhibited the differentiation of the cells induced by dexamethasone or a protein inducer.”