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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dexamethasone
supplement:
Tryptophan
Research Papers that Mention the Interaction
“ Tryptophan and L -dopa loading was found to raise the sensitivity of the hypothalamo-pituitary complex to inhibition by dexamethasone.”
Hypothalamic mechanisms of ageing and of specific age pathology—II. On the sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in adaptive homeostasis“The results demonstrate a stimulatory effect of l-tryptophan on prolactin and growth hormone secretion, and the former is facilitated by pretreatment with dexamethasone.”
“Pharmacological enhancement of serotoninergic processes with alpha-tryptophan either increased or decreased the inhibitory effect of dexamethasone with relation to the initial response to glucocorticoid administration.”
“It has recently been reported that the administration of a dose of dexamethasone sufficient to cause cortisol suppression also caused significant decrements in the availability of L-TRP.”
“ Postdexamethasone L-TRP and FFA levels were significantly and positively correlated.”
“The baseline disposal of L-TRP was related neither to insulin nor to FFA concentrations Dexamethasone administration significantly reduced the L-TRP and L-TRP/CAA values and increased FFA and insulin levels.”
“Accordingly, the plasma ratios between L‐TRP and tyrosine and the sum of the competing amino acids were significantly reduced by dexamethasone administration.”
“We found significantly decreased plasma L‐TRP and tyrosine levels after treatment with dexamethasone compared with basal levels.”
“The cortisol responses to dexamethasone were significantly and negatively correlated with the availability of L-TRP.”
“Removal of DEX also induced the expression of several genes involved in the biosynthesis of tryptophan and the auxin, indole‐3‐acetic acid (IAA).”
Cellular localization of the Arabidopsis class 2 phytoglobin influences somatic embryogenesis
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