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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dexamethasone
supplement:
Thiamine
Research Papers that Mention the Interaction
“CONCLUSIONS Riboflavin and th amine ex acerbate the anti-inflammatory activity of dex amethasone an d reduce production of TNF-α and IL-6.”
“Riboflavin (500mg/kg) and thiamine (600mg/kg) exacerbated the anti-inflammatory activity of dexamethasone.”
“The association of dexamethasone with thiamine induced greater inhibition of IL-6 production when compared with that induced by dexamethasone.”
Thiamine and riboflavin inhibit production of cytokines and increase the anti-inflammatory activity of a corticosteroid in a chronic model of inflammation induced by complete Freund's adjuvant.“Coadministration of thiamine or cyanocobalamin and dexamethasone remarkably reduced spinal nerve ligation induced allodynia (∼90%), showing a synergistic interaction between either thiamine or cyanocobalamin and dexamethasone.”
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