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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Dexamethasone
supplement:
Iodides
Research Papers that Mention the Interaction
“After incubation with Dex, iodide accumulation in NP-1 cells increased up to 1.5-fold, whereas NIS mRNA and protein expression levels were increased up to 1.7-fold.”
“In conclusion, in addition to an antiproliferative effect, treatment with Dex increases androgen-dependent NIS mRNA and protein expression as well as iodide accumulation, resulting in an increased cytotoxic effect of 131-I in prostate cancer cells stably expressing NIS under the control of the PSA-promoter.”
Dexamethasone enhances the cytotoxic effect of radioiodine therapy in prostate cancer cells expressing the sodium iodide symporter.“ Iodide accumulation was decreased by up to 40% after incubation with dexamethasone and T3, respectively, in a concentration-dependent manner.”
Regulation of sodium iodide symporter gene expression in FRTL-5 rat thyroid cells.“After administration of dexamethasone , the iodide concentration process in the gastric mucosa is not affected, but the organification of iodide is significantly diminished.”
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